Could not load file or assembly AppCode.opqcfopj Version0.0.0.0 Cultureneutral PublicKey

while running my project its shows an error like this.please help me..

Error    1    Could not load file or assembly 'App_Code.opqcfopj, Version=0.0.0.0, Culture=neutral, PublicKeyToken=null' or one of its dependencies. Access is denied.